Neonatal red cell transfusions

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Red cell transfusions for polytransfused patients.

Patients with chronic anemia tolerate much lower levels of hemoglobin than those experiencing acute blood loss or acute hemolysis. The compensating mechanism is the increase of red cell 2,3-diphosphoglycerate (DPG), causing increased release of oxygen to the tissues. For this and further clinical and epidemiologic reasons, it is unnecessary to transfuse patients with chronic anemia unless sympt...

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Costs of outpatient red blood cell transfusions.

W ith the goals of improving oxygen delivery,1 reducing anemia, and enhancing quality of life, over 12 million red blood cell (RBC) units are transfused annually in the United States.2 At a hospital acquisition cost per RBC unit of $122 (1999 dollars),2 US acquisition costs exceed $1.5 billion annually. Adding testing and transfusion, the total health system cost for two units (based on prior s...

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Red blood cell transfusions in acute paediatrics.

Red blood cell (RBC) transfusions should usually be given only to restore or maintain oxygen delivery to vital organs and tissues. Medical history has clearly documented the importance of blood transfusion in saving lives threatened by acute haemorrhage or severe anaemia. The availability of blood products has facilitated many surgical and medical advances, allowing the support of patients who ...

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Adverse effects of small-volume red blood cell transfusions in the neonatal population

BACKGROUND Adverse transfusion reactions in the neonatal population are poorly understood and defined. The incidence and pattern of adverse effects due to red blood cell (RBC) transfusion are not well known, and there has been no systematic review of published adverse events. RBC transfusions continue to be linked to the development of morbidities unique to neonates, including chronic lung dise...

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Serial assessment of biochemical parameters of red cell preparations to evaluate safety for neonatal transfusions

BACKGROUND AND OBJECTIVES Neonatologists often prefer fresh blood (<7 days) for neonatal transfusions. The main concerns for stored RBCs are ex vivo storage lesions that undermine red cell functions and may affect metabolic status of neonatal recipients. This study was designed to evaluate serial in vitro changes of biochemical parameters in different RBC preparations during storage to consider...

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ژورنال

عنوان ژورنال: Immunohematology

سال: 2020

ISSN: 0894-203X,1930-3955

DOI: 10.21307/immunohematology-2019-257